For which type of tumors is VTP primarily indicated?

Vascular Targeted Photodynamic Therapy (VTP) is primarily indicated for surface tumors, such as skin cancer. This treatment modality leverages the interaction between photosensitizing agents and light to selectively target tumor vasculature, leading to the destruction of tumor cells while sparing the surrounding healthy tissue.

Surface tumors are particularly well-suited for VTP because they are accessible to both the photosensitizer and the light source used in the treatment. The effectiveness of VTP is maximized when the tumor can be visualized and illuminated directly, allowing the photodynamic reaction to occur efficiently.

In contrast, internal tumors, brain tumors, or lung tumors may present challenges for VTP due to factors such as depth of the tumors, difficulty in accessing them for treatment, and the potential for damage to surrounding vital tissues and organs. The treatment has been primarily developed and refined for conditions like skin cancer, where the advantages of VTP can be fully realized.