What is the significance of light dosimetry in VTP?

The significance of light dosimetry in Vascular Targeted Photodynamic (VTP) therapy is centered on ensuring the appropriate amount of light reaches the tumor. In VTP, light is used to activate photosensitizers that have been preferentially accumulated in tumor tissues. The effectiveness of the treatment relies heavily on the dose of light delivered to these areas, as insufficient light may not effectively activate the photosensitizer, while excessive light could lead to unwanted damage to surrounding healthy tissues or result in reduced effectiveness.

By carefully measuring and controlling the light dose, practitioners can optimize the treatment outcome, maximizing tumor destruction while minimizing side effects. This meticulous dosimetry is essential for achieving the desired therapeutic effect, highlighting its critical role in successful VTP procedures.