What role does near-infrared imaging play in VTP?

Near-infrared imaging plays a crucial role in Vascular Targeted Photodynamic (VTP) therapy by allowing for the visualization of photosensitizer presence in tissues. Photosensitizers are compounds used in photodynamic therapy that become activated by specific wavelengths of light. When these compounds are introduced into the body, near-infrared imaging enables clinicians to detect and visualize areas where the photosensitizer accumulates, particularly within tumors or abnormal vascular structures.

This visualization is vital as it helps to confirm that the photosensitizers are localized appropriately within the target tissues before the activation phase. Proper localization ensures that the therapy can be effective in targeting cancerous tissues while minimizing damage to surrounding healthy tissues. Thus, near-infrared imaging serves as an essential tool for assessing the effectiveness of the treatment by confirming the presence and distribution of the photosensitizer in the target area.